• <a href=https://www.ycombinator.com/"https://www.linkedin.com/in/debergalis//">Matt DeBergalis</strong></a>, co-founder of <a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/apollo/">Apollo GraphQL</a> (valued over $1B)<br>• <a href=https://www.ycombinator.com/"https://www.linkedin.com/in/umurc//">Umur Cubukcu</strong></a>, co-founder of <a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/citus-data/">Citus Data</a> (acquired by Microsoft) and now Visiting Group Partner at Y Combinator<br>• <a href=https://www.ycombinator.com/"https://www.linkedin.com/in/reshmakhilnani//">Reshma Khilnani</strong></a>, co-founder of <a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/medplum/">MedPlum and former Visiting Group Partner at Y Combinator</p><p>and also a short talk from Daniel Gackle who runs <a href=https://www.ycombinator.com/"https://news.ycombinator.com//">Hacker News</a>.</p><p>After the panel, we’ll have a cocktail reception. We’ve invited many other founders of YC Open Source Software companies so you can get to know them 1-1. YC Group Partners will be around if you want to bounce around ideas about possible startups.</p><p>We have limited space and expect the event to be over-subscribed. Please complete the form below, and we’ll reach out if we can offer you a spot at the event.</p><!--kg-card-begin: html--><center>\n<a class=\"ycdc-retro-btn ycdc-retro-btn-gold mt-[-10px] ml-[13px]\" href=https://www.ycombinator.com/"https://apply.ycombinator.com/events/346/" style=\"text-decoration: none;\" title=\"title for your link\" target=\"_blank\">Apply to attend</a>\n</center><!--kg-card-end: html-->","comment_id":"6413474fc1abdc000107c9f8","feature_image":"/blog/content/images/2023/03/asdfads.png","featured":true,"visibility":"public","email_recipient_filter":"none","created_at":"2023-03-16T09:43:59.000-07:00","updated_at":"2023-03-20T07:06:10.000-07:00","published_at":"2023-03-16T14:47:26.000-07:00","custom_excerpt":"We're hosting a meetup for Open Source Software startups! YC has funded over 75 OSS companies to date and we’re especially excited about them. 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We've funded over 75 OSS companies to date and we’re especially excited about them.","reading_time":1,"access":true,"og_image":null,"og_title":null,"og_description":null,"twitter_image":null,"twitter_title":null,"twitter_description":null,"meta_title":null,"meta_description":null,"email_subject":null,"frontmatter":null,"feature_image_alt":null,"feature_image_caption":null},{"id":"638559cc3a008e000176edd4","uuid":"e7d13ed0-72da-46aa-a877-cb21bda20645","title":"YC Happy Hour at the JP Morgan Healthcare Conference","slug":"yc-happy-hour-at-jp-morgan-healthcare-conference","html":"<p>Join us for a happy hour during the JP Morgan Healthcare Conference. </p><p>If you’re a YC alum, an investor, industry leader, or are interested in starting a bio or healthcare company, we’d love to see you there.</p><p><strong>YC at JPM</strong><br>January 10 from 2:30 - 5 pm in San Francisco, CA<br>Appetizers and drinks will be served. <br><br>Space is limited, so sign up <a href=https://www.ycombinator.com/"https://docs.google.com/forms/d/e/1FAIpQLSdtMLHJC2orF1Ua8PAz4V20IZCeHTtTbNdESZtXU84QUPYL8w/viewform?usp=sf_link\%22>here by December 29 and we’ll send you a confirmation and location details by December 30.</p><!--kg-card-begin: html--><center>\n<a class=\"ycdc-retro-btn ycdc-retro-btn-gold mt-[-10px] ml-[13px]\" href=https://www.ycombinator.com/"https://docs.google.com/forms/d/e/1FAIpQLSdtMLHJC2orF1Ua8PAz4V20IZCeHTtTbNdESZtXU84QUPYL8w/viewform/" style=\"text-decoration: none;\" title=\"YC Happy Hour at JP Morgan Healthcare Conference\" target=\"_blank\">Sign Up</a>\n</center><!--kg-card-end: html-->","comment_id":"638559cc3a008e000176edd4","feature_image":"/blog/content/images/2022/11/BlogTwitter-Image-Template--31-.png","featured":true,"visibility":"public","email_recipient_filter":"none","created_at":"2022-11-28T17:01:00.000-08:00","updated_at":"2022-11-29T08:51:35.000-08:00","published_at":"2022-11-29T08:51:00.000-08:00","custom_excerpt":"Join us for a happy hour during the JP Morgan Healthcare Conference in San Francisco on January 10th. 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","reading_time":1,"access":true,"og_image":null,"og_title":null,"og_description":null,"twitter_image":null,"twitter_title":null,"twitter_description":null,"meta_title":null,"meta_description":null,"email_subject":null,"frontmatter":null,"feature_image_alt":null,"feature_image_caption":null},{"id":"63f91878d2b0220001e8d6e9","uuid":"a99f2458-1bdd-4a40-81e6-36ee441b133c","title":"Congratulations to the 2023 YC Top Companies!","slug":"yc-top-companies-feb-2023","html":"<p>We’re excited to present the 2023 YC Top Companies!</p><p>The startups are separated into 3 lists: YC’s top <a href=https://www.ycombinator.com/"https://www.ycombinator.com/topcompanies/" rel=\"noopener noreferrer\">private</a>, <a href=https://www.ycombinator.com/"https://www.ycombinator.com/topcompanies/public/" rel=\"noopener noreferrer\">public</a>, and <a href=https://www.ycombinator.com/"https://www.ycombinator.com/topcompanies/exits/" rel=\"noopener noreferrer\">exited</a>. 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Public companies are listed in alphabetical order.</p><p>The Breakthrough Companies list highlights the fast-growing companies we’ve doubled down on – which means they’ve all received significant additional investment from YC in their post-Demo Day rounds. </p><p><strong>Here are stats about the companies on this year’s list:</strong></p><p><strong>></strong> More than 290 private YC companies and 33 exits are valued at over $150M, over 90 are worth more than $1B, and 16 are public. </p><p><strong>></strong> 58% of the companies have HQs in the Bay Area. 27% of the companies are fully remote, and 55% list themselves as partially remote.</p><p><strong>></strong> YC Top Companies have HQs in 40 countries including: United States, India, United Kingdom, Canada, Colombia, Indonesia, Mexico, Nigeria, Argentina, Brazil, Chile, France, Spain, Israel, Netherlands, Philippines, Portugal, Germany, Egypt, Ireland, South Korea, Peru, Singapore, United Arab Emirates, Australia, Bolivia, Switzerland, Algeria, Estonia, Finland, Hungary, Italy, Norway, Romania, Sweden, Senegal, Uganda, Uruguay, Venezuela, Vietnam</p><p><strong>></strong> YC W16 is the most represented batch (by percentage). 23% of the companies from W16 are on the YC Top Companies list. </p><p><strong>></strong> Here’s a sector breakdown of the top companies:</p><ul><li>B2B Software and Services: 43%</li><li>Financial Technology and Services: 19%</li><li>Consumer: 13%</li><li>Healthcare: 12%</li><li>Industrials: 7%</li><li>Real Estate and Construction: 3%</li><li>Education and Government: 3%</li></ul><p><strong>></strong> 10 new companies joined the lists since August 2022:</p><p>Private:</p><ul><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/treasury-prime/">Treasury Prime</a> (YC W18) - Embedded banking software platform and marketplace</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/onesignal/">OneSignal (YC S11) - Engage customers through personalized omni-channel messaging</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/skill-lync/">Skill-lync (YC W19) - Online engineering college for India</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/tigereye/">TigerEye (YC S22) - Modern enterprise software for sales leaders</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/zeitview/">Zeitview (YC W15) - Inspection software for renewable energy & sustainable infrastructure</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/ontop/">OnTop (YC W21) - A bank for remote workers connected to payroll</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/obie/">Obie (YC S19) - Insurance and risk management for landlords</li><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/nabis/">Nabis (YC W19) - The largest licensed cannabis wholesale platform</li></ul><p>Public:</p><ul><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/presto/">Presto (YC S10) - Digital meets physical for big chain restaurants</li></ul><p>Exits:</p><ul><li><a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/nurx/">NURX (YC W16) - Medicine or testing kit, prescribed online, and delivered to your door </li></ul><p>One thing to note is that this is not an exhaustive list of YC’s top companies. We allowed founders to opt out of being listed for any reason. The full list of YC companies can be found <a href=https://www.ycombinator.com/"https://www.ycombinator.com/companies/">here. </p><p>Congrats again to the companies recognized on the 2023 YC Top Companies list!</p>","comment_id":"63f91878d2b0220001e8d6e9","feature_image":"/blog/content/images/2023/02/BlogTwitter-Image-Template.png","featured":true,"visibility":"public","email_recipient_filter":"none","created_at":"2023-02-24T12:05:12.000-08:00","updated_at":"2023-03-16T09:44:58.000-07:00","published_at":"2023-02-27T09:00:00.000-08:00","custom_excerpt":"There are now 16 public YC companies, 290 private YC companies and 33 exits that are valued at over $150M, and over 80 that are worth more than $1B.","codeinjection_head":null,"codeinjection_foot":null,"custom_template":null,"canonical_url":null,"authors":[{"id":"61fe29e3c7139e0001a7106f","name":"Y 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YC Partners With Atomwise to Fund More Bio Companies
by Jared Friedman4/29/2019
In the last 10 years, the tools for studying biology have become much less expensive and more widely available. This has made it possible for new startups to do serious research right from the start, and it is leading to an explosion of biotech startups.
One of the key tools that has brought down the cost of developing drugs is computational drug discovery. Until recently, the primary way drug companies found new drugs was by trying millions of chemical compounds, hoping one would work, and laboriously iterating their way to a drug. Atomwise (which is a YC company) is able to do those experiments in simulation on a computer, testing billions of compounds dramatically cheaper, faster, and far beyond the capability of physical screening.
About two years ago, Atomwise started the Artificial Intelligence Molecular Screen (AIMS) Awards program, which I think is a game changer. AIMS gives away Atomwise’s drug discovery service for free to researchers in academia. Today, when researchers at a university discover a promising opportunity for a new drug (in scientific terms, a “target”), they’re stuck in a catch-22. They need to raise funding to pay for drug discovery to find the right drug, but it’s hard to raise investment until they’ve found a compelling lead molecule! AIMS solves the catch-22.
AIMS has already helped over 200 researchers discover small molecule leads in diverse areas, including oncology, infectious diseases, metabolic disorders, and neurology. I believe this is the tip of the iceberg, and AIMS can unlock thousands of promising therapeutics ideas that would otherwise never have been developed.
Once researchers work with AIMS to develop drug candidates, the next step is to turn the research into a company. That’s where YC comes in. We’re going to work with Atomwise to give interested AIMS teams an expedited path to joining YC. For AIMS teams that want YC funding, we’ll guide them through the YC application process and prioritize their applications. For AIMS teams that we accept, we’ll invest in them, help them incorporate, and help them with the initial stages of commercialization – everything from figuring out their regulatory strategy to getting lab space.
In addition, Atomwise is going to make the free drug discovery service they pioneered in the AIMS program available as a benefit to all YC companies. This should help any YC company to develop a small molecule program faster than any other existing option.
We believe this is the golden age of drug discovery, and we’re thrilled to partner with Atomwise. The application deadline for Atomwise’s AIMS Awards program is May 31— and YC applications are always open.
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Author
Jared Friedman
Jared is Managing Director, Software and Group Partner at YC. He was cofounder of Scribd, which was funded by Y Combinator in 2006 and grew to be one of the top 100 sites on the web.